How many days will we not have an infection after having corona? I have had both Corona doses, for how long am I safe with Corona now?
Answers to both these questions related to Corona have been searched in America. According to two studies published in the science journal Nature recently, immunity against corona persists for at least one year to life in most cases. This immunity is further improved after vaccination.
People recovering from Corona do not need a booster dose of vaccine
It clearly shows in both studies that most people who have recovered from corona, who later get the vaccine, will not need a booster dose. However, people who do not get infected or who do not develop strong immunity despite being infected will need boosters or other doses. However, the number of such people is very less.
Both reports studied people who had corona a year earlier.
Cells that remember the virus make antibodies when needed
According to the first reports of Washington University's Jackson S. Turner, Elizaveta Kalidina, Charles W. Goss, etc., the virus-remembering cells persist in bone-like tissues within the bone marrow and start producing antibodies when needed.
According to the second research posted online on the biology research website BioRxiv, these cells called B cells to continue to mature and grow for at least 12 months after infection.
Immunity due to infection or vaccination of the corona lasts for a long time.
Immunologist Scott Hensley at the University of Pennsylvania says that both of these research papers are consistent with research that suggests that immunity from corona infection or vaccination persists for a long time.
Without booster doses, B cells thwart the variants of the virus.
Immunologist Michelle Nassenweg of Rockefeller University in New York says that B cells that grow stronger because of coronation infection are so strong that they can thwart the variants of the virus without the booster dose.
Rockefeller has researched the memory maturation of cells.
Dr. Nussenweg says that people who had a corona and also got vaccinated had tremendous antibodies because their antibodies also continue to develop. These antibodies are expected to last for a long time.
Those who are not corona need a booster dose after the vaccine
Dr. Nussenweg also said that such results would not be seen only among vaccine users, because immune memory works differently in immunity from immunity than in naturally occurring infections. This means that if no one has a corona and has been vaccinated, they will need a booster dose.
Researchers, led by Ali Albedy of Washington University in St. Louis, analyzed blood for 77 people who had been infected with the corona at intervals of three months, to look for specific B cells for the new coronavirus.
Of these 77, only 6 people were hospitalized due to severe corona infection, all of whom had mild symptoms of the corona. Antibody levels in these individuals declined rapidly until four months after infection and continued to decrease gradually for the following months.
Antibody Phenomenon Weak Immunity
Some scientists have described this decrease of antibodies as a weak immunity. At the same time, some other experts say that this is expected. If antibodies are high in the blood, it quickly turns into a thick sludge.
Dr. Allebedy says that everyone should apply the corona vaccine, even if they have been infected with corona. Being infected does not mean that you have a super immune system.
Five of the participants in Dr. Allebedy's study donated a bone marrow seven or eight months after being infected. In which he found that B cells were still stable in his bone marrow.
Antibodies can persist throughout their life
A historical study conducted in 2007 showed that antibodies could survive for decades, perhaps even longer than the average lifespan. This is an indication that memory B cells are long-lived.
Dr. Nussenweg's team closely observed how B cells mature over time. Researchers analyzed the blood of 63 people who had recovered from Covid-19 about a year ago. Most people had mild symptoms and 26 had undergone at least one dose of the Moderna or Pfizer-BioNotech vaccine.
Neutralizing antibodies do not change even between 6 and 12 months
Dr. Nussenweg's team found that the neutralizing antibodies needed to prevent recurrence do not change between 6 to 12 months. While related but less important antibodies gradually disappeared.
The results of Dr. Nussenweg's study say that people who have been infected with the corona and have also been vaccinated have a longer ability to fight dangerous variants of the virus without a vaccine booster.
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